Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hitHistidine triad (HIT) protein. (140 aa)    
Predicted Functional Partners:
puuA
Glutamine synthase; Belongs to the glutamine synthetase family.
   
   0.731
glnA
Glutamine synthetase.
   
   0.731
Lgra_0905
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.620
lysS
lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.540
Lgra_0906
Prolyl oligopeptidase; Belongs to the UPF0255 family.
       0.535
udk_1
Uridine kinase.
    
  0.482
udk_2
Uridine kinase.
    
  0.482
bcp
Acetylpolyamine aminohydrolase.
    
  0.455
btuE
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
   0.401
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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