STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lgrB_1Non-ribosomal peptide synthase. (615 aa)    
Predicted Functional Partners:
tycC_2
Peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  0.983
pksJ_1
Polyketide synthase, type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.979
Lgra_2195
acyl-CoA synthetase.
 0.979
lgrB_2
Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 0.944
pksJ_2
Polyketide synthase module; Belongs to the ATP-dependent AMP-binding enzyme family.
 0.938
pksM
Polyketide synthase.
 
 0.918
Lgra_1551
Saframycin Mx1 synthetase B.
 
 0.850
psf-1
Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
 
 
 0.791
lgrD
Peptide synthetase, non-ribosomal.
 
  0.777
Lgra_0544
Polyketide synthase.
 
 
0.745
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
Server load: low (26%) [HD]