| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lgra_2215 | bvgS | Lgra_2215 | Lgra_1355 | DNA internalization-related competence protein ComEC/Rec2. | Sensory box histidine kinase/response regulator. | 0.496 |
| Lgra_2215 | nadD | Lgra_2215 | Lgra_2564 | DNA internalization-related competence protein ComEC/Rec2. | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.443 |
| Lgra_2215 | rsfS | Lgra_2215 | Lgra_3219 | DNA internalization-related competence protein ComEC/Rec2. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.443 |
| Lgra_2215 | yhbY | Lgra_2215 | Lgra_1008 | DNA internalization-related competence protein ComEC/Rec2. | RNA-binding protein. | 0.472 |
| bvgS | Lgra_2215 | Lgra_1355 | Lgra_2215 | Sensory box histidine kinase/response regulator. | DNA internalization-related competence protein ComEC/Rec2. | 0.496 |
| bvgS | yhbY | Lgra_1355 | Lgra_1008 | Sensory box histidine kinase/response regulator. | RNA-binding protein. | 0.455 |
| ftsH_1 | msrA_1 | Lgra_1006 | Lgra_1004 | Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.822 |
| ftsH_1 | pgsA2 | Lgra_1006 | Lgra_1009 | Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.437 |
| ftsH_1 | rplK | Lgra_1006 | Lgra_0358 | Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.711 |
| ftsH_1 | rrmJ | Lgra_1006 | Lgra_1007 | Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Ribosomal RNA large subunit methyltransferase (cell division protein FtsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.919 |
| ftsH_1 | yhbY | Lgra_1006 | Lgra_1008 | Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | RNA-binding protein. | 0.647 |
| hda | pgsA2 | Lgra_1010 | Lgra_1009 | ATPase regulatory factor involved in DnaA inactivation; Belongs to the DnaA family. HdA subfamily. | Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.845 |
| hda | rrmJ | Lgra_1010 | Lgra_1007 | ATPase regulatory factor involved in DnaA inactivation; Belongs to the DnaA family. HdA subfamily. | Ribosomal RNA large subunit methyltransferase (cell division protein FtsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.428 |
| hda | yhbY | Lgra_1010 | Lgra_1008 | ATPase regulatory factor involved in DnaA inactivation; Belongs to the DnaA family. HdA subfamily. | RNA-binding protein. | 0.692 |
| msrA_1 | ftsH_1 | Lgra_1004 | Lgra_1006 | Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.822 |
| msrA_1 | pgsA2 | Lgra_1004 | Lgra_1009 | Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.421 |
| msrA_1 | rrmJ | Lgra_1004 | Lgra_1007 | Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Ribosomal RNA large subunit methyltransferase (cell division protein FtsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.712 |
| msrA_1 | yhbY | Lgra_1004 | Lgra_1008 | Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | RNA-binding protein. | 0.624 |
| nadD | Lgra_2215 | Lgra_2564 | Lgra_2215 | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | DNA internalization-related competence protein ComEC/Rec2. | 0.443 |
| nadD | rsfS | Lgra_2564 | Lgra_3219 | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.804 |