hsrA_1 protein (Legionella gratiana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

hsrA_1

Multidrug efflux protein; Belongs to the major facilitator superfamily. (465 aa)

Predicted Functional Partners:

emrA_2

0.825

emrA_1

0.806

yibH_1

0.684

yibH_2

0.572

yiaV_1

0.560

rep

0.542

yiaV_2

0.490

sflR

0.461

bcr_3

0.447

cspC_1

0.428

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
bcr_3	hsrA_1	Lgra_1626	Lgra_1035	Major facilitator superfamily (MFS) transporter.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.447
cspC_1	hsrA_1	Lgra_1036	Lgra_1035	Stress protein, member of the CspA-family.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.428
emrA_1	hsrA_1	Lgra_0155	Lgra_1035	Multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.806
emrA_2	hsrA_1	Lgra_1767	Lgra_1035	Multidrug efflux system.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.825
hsrA_1	bcr_3	Lgra_1035	Lgra_1626	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Major facilitator superfamily (MFS) transporter.	0.447
hsrA_1	cspC_1	Lgra_1035	Lgra_1036	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Stress protein, member of the CspA-family.	0.428
hsrA_1	emrA_1	Lgra_1035	Lgra_0155	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.806
hsrA_1	emrA_2	Lgra_1035	Lgra_1767	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Multidrug efflux system.	0.825
hsrA_1	rep	Lgra_1035	Lgra_1034	Multidrug efflux protein; Belongs to the major facilitator superfamily.	ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.	0.542
hsrA_1	sflR	Lgra_1035	Lgra_2385	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Florfenicol efflux pump-like protein.	0.461
hsrA_1	yiaV_1	Lgra_1035	Lgra_2412	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Hemolysin D.	0.560
hsrA_1	yiaV_2	Lgra_1035	Lgra_0857	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Hemolysin D.	0.490
hsrA_1	yibH_1	Lgra_1035	Lgra_2362	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Hemolysin D.	0.684
hsrA_1	yibH_2	Lgra_1035	Lgra_1537	Multidrug efflux protein; Belongs to the major facilitator superfamily.	Hemolysin D.	0.572
rep	hsrA_1	Lgra_1034	Lgra_1035	ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.542
sflR	hsrA_1	Lgra_2385	Lgra_1035	Florfenicol efflux pump-like protein.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.461
yiaV_1	hsrA_1	Lgra_2412	Lgra_1035	Hemolysin D.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.560
yiaV_2	hsrA_1	Lgra_0857	Lgra_1035	Hemolysin D.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.490
yibH_1	hsrA_1	Lgra_2362	Lgra_1035	Hemolysin D.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.684
yibH_2	hsrA_1	Lgra_1537	Lgra_1035	Hemolysin D.	Multidrug efflux protein; Belongs to the major facilitator superfamily.	0.572