node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lgra_1056 | clcA_1 | Lgra_1056 | Lgra_1054 | Hypothetical protein. | Chloride channel protein. | 0.616 |
Lgra_1056 | ribE | Lgra_1056 | Lgra_1055 | Hypothetical protein. | Riboflavin synthase alpha chain. | 0.795 |
Lgra_1056 | yciA | Lgra_1056 | Lgra_1057 | Hypothetical protein. | Hydrolase. | 0.795 |
acsB | fadB | Lgra_1468 | Lgra_2557 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.914 |
acsB | succ | Lgra_1468 | Lgra_0638 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.683 |
acsB | ybgC | Lgra_1468 | Lgra_2136 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | acyl-CoA thioesterase. | 0.474 |
acsB | yciA | Lgra_1468 | Lgra_1057 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hydrolase. | 0.511 |
acsB | yfcX | Lgra_1468 | Lgra_0258 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.914 |
clcA_1 | Lgra_1056 | Lgra_1054 | Lgra_1056 | Chloride channel protein. | Hypothetical protein. | 0.616 |
clcA_1 | ribE | Lgra_1054 | Lgra_1055 | Chloride channel protein. | Riboflavin synthase alpha chain. | 0.616 |
clcA_1 | yciA | Lgra_1054 | Lgra_1057 | Chloride channel protein. | Hydrolase. | 0.616 |
fadB | acsB | Lgra_2557 | Lgra_1468 | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.914 |
fadB | fcbC | Lgra_2557 | Lgra_1092 | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | Thiesterase. | 0.783 |
fadB | succ | Lgra_2557 | Lgra_0638 | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.594 |
fadB | tdh | Lgra_2557 | Lgra_2180 | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | Threonine(-3-)dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.591 |
fadB | ybgC | Lgra_2557 | Lgra_2136 | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | acyl-CoA thioesterase. | 0.755 |
fadB | yciA | Lgra_2557 | Lgra_1057 | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | Hydrolase. | 0.786 |
fadB | yfcX | Lgra_2557 | Lgra_0258 | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.849 |
fcbC | fadB | Lgra_1092 | Lgra_2557 | Thiesterase. | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.783 |
fcbC | yciA | Lgra_1092 | Lgra_1057 | Thiesterase. | Hydrolase. | 0.517 |