STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lgra_1139Putative helicase/relaxase. (446 aa)    
Predicted Functional Partners:
tolR
Membrane spanning protein in TolA-TolQ-TolR complex; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.959
Lgra_1137
Outer membrane efflux protein.
 
  
  0.941
tolQ
Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.940
acrA_1
Membrane-fusion protein AcrA.
 
  
  0.903
macB_1
Putative fused transporter subunits of ABC superfamily: ATP-binding component.
     
 0.847
macB_2
ABC transporter permease.
     
 0.842
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
       0.842
secA_3
Coiled-coil protein.
 
  
  0.799
dotA
Defect in organelle trafficking protein DotA.
  
     0.770
ksgA
Dimethyladenosine transferase (16S rRNA dimethylase); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
       0.761
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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