Lgra_1199 protein (Legionella gratiana) - STRING interaction network

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Score

Lgra_1199

Substrate of the Dot/Icm secretion system. (507 aa)

Predicted Functional Partners:

dnaK

0.889

Lgra_2421

0.874

Lgra_2656

0.854

htpG

0.843

grpE

0.788

Lgra_2195

0.787

Lgra_1551

0.779

tycC_1

0.778

htpB

0.778

Lgra_0492

0.633

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lgra_0492	Lgra_1199	Lgra_0492	Lgra_1199	PPR repeat protein.	Substrate of the Dot/Icm secretion system.	0.633
Lgra_0492	Lgra_1551	Lgra_0492	Lgra_1551	PPR repeat protein.	Saframycin Mx1 synthetase B.	0.756
Lgra_0492	Lgra_2195	Lgra_0492	Lgra_2195	PPR repeat protein.	acyl-CoA synthetase.	0.795
Lgra_0492	Lgra_2421	Lgra_0492	Lgra_2421	PPR repeat protein.	Ras family protein.	0.953
Lgra_0492	Lgra_2656	Lgra_0492	Lgra_2656	PPR repeat protein.	Ankyrin repeat-containing protein.	0.943
Lgra_0492	dnaK	Lgra_0492	Lgra_2296	PPR repeat protein.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.943
Lgra_0492	htpB	Lgra_0492	Lgra_0793	PPR repeat protein.	Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.682
Lgra_0492	htpG	Lgra_0492	Lgra_3229	PPR repeat protein.	Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.	0.911
Lgra_0492	tycC_1	Lgra_0492	Lgra_0545	PPR repeat protein.	Non-ribosomal peptide synthase.	0.668
Lgra_1199	Lgra_0492	Lgra_1199	Lgra_0492	Substrate of the Dot/Icm secretion system.	PPR repeat protein.	0.633
Lgra_1199	Lgra_1551	Lgra_1199	Lgra_1551	Substrate of the Dot/Icm secretion system.	Saframycin Mx1 synthetase B.	0.779
Lgra_1199	Lgra_2195	Lgra_1199	Lgra_2195	Substrate of the Dot/Icm secretion system.	acyl-CoA synthetase.	0.787
Lgra_1199	Lgra_2421	Lgra_1199	Lgra_2421	Substrate of the Dot/Icm secretion system.	Ras family protein.	0.874
Lgra_1199	Lgra_2656	Lgra_1199	Lgra_2656	Substrate of the Dot/Icm secretion system.	Ankyrin repeat-containing protein.	0.854
Lgra_1199	dnaK	Lgra_1199	Lgra_2296	Substrate of the Dot/Icm secretion system.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.889
Lgra_1199	grpE	Lgra_1199	Lgra_2295	Substrate of the Dot/Icm secretion system.	Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]	0.788
Lgra_1199	htpB	Lgra_1199	Lgra_0793	Substrate of the Dot/Icm secretion system.	Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.778
Lgra_1199	htpG	Lgra_1199	Lgra_3229	Substrate of the Dot/Icm secretion system.	Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.	0.843
Lgra_1199	tycC_1	Lgra_1199	Lgra_0545	Substrate of the Dot/Icm secretion system.	Non-ribosomal peptide synthase.	0.778
Lgra_1551	Lgra_0492	Lgra_1551	Lgra_0492	Saframycin Mx1 synthetase B.	PPR repeat protein.	0.756