STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpxA_4Sensor histidine kinase. (558 aa)    
Predicted Functional Partners:
cpxR_2
Transcriptional regulatory protein CpxR.
 
 0.974
arcB_3
Sensory histidine-kinase / response regulator.
 
 
 0.969
evgS
Sensory box histidine kinase/response regulator.
 
0.950
bvgS
Sensory box histidine kinase/response regulator.
 
 
0.938
luxQ
Sensor histidine kinase.
 
0.889
ompR_1
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 0.869
ompR_3
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 0.867
cyaB
Guanylate/adenylate cyclase.
 
 0.855
ompR_2
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 0.848
cpxR_1
Transcriptional regulatory protein CpxR.
 
 0.836
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
Server load: low (16%) [HD]