Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lgra_1334Cyclic nucleotide-binding protein. (370 aa)    
Predicted Functional Partners:
cyaA_1
Guanylate cyclase.
 
 
 0.838
Lgra_2421
Ras family protein.
    
  0.827
cyaB
Guanylate/adenylate cyclase.
 
 0.793
cyaA_3
Guanylate cyclase.
 
 
 0.790
Lgra_1333
Hypothetical protein.
       0.776
Lgra_1335
Reverse transcriptase (RNA-dependent DNA polymerase).
       0.773
crp
Cyclic nucleotide-binding protein.
  
     0.745
cyaA_2
Guanylate cyclase.
  
 
  0.743
Lgra_3377
cNMP binding domain-containing protein.
  
     0.736
cya
Guanylate cyclase.
  
 
  0.683
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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