aes protein (Legionella gratiana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

aes

Lipase. (323 aa)

Predicted Functional Partners:

Lgra_2195

0.924

Lgra_1551

0.893

tycC_1

0.804

nqo1

0.738

nuoI

0.725

pksJ_2

0.700

nuoE

0.697

nuoG

0.639

petC

0.614

petA

0.558

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lgra_1551	Lgra_2195	Lgra_1551	Lgra_2195	Saframycin Mx1 synthetase B.	acyl-CoA synthetase.	0.998
Lgra_1551	aes	Lgra_1551	Lgra_1356	Saframycin Mx1 synthetase B.	Lipase.	0.893
Lgra_1551	nqo1	Lgra_1551	Lgra_0996	Saframycin Mx1 synthetase B.	NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.	0.879
Lgra_1551	nuoE	Lgra_1551	Lgra_0997	Saframycin Mx1 synthetase B.	NADH dehydrogenase I chain E.	0.886
Lgra_1551	nuoG	Lgra_1551	Lgra_0995	Saframycin Mx1 synthetase B.	NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.	0.913
Lgra_1551	nuoI	Lgra_1551	Lgra_0993	Saframycin Mx1 synthetase B.	NADH-quinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.904
Lgra_1551	petA	Lgra_1551	Lgra_0698	Saframycin Mx1 synthetase B.	Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.	0.881
Lgra_1551	petC	Lgra_1551	Lgra_0696	Saframycin Mx1 synthetase B.	Ubiquinol-cytochrome c oxydoreductase, cytochrome c1.	0.863
Lgra_1551	pksJ_2	Lgra_1551	Lgra_1354	Saframycin Mx1 synthetase B.	Polyketide synthase module; Belongs to the ATP-dependent AMP-binding enzyme family.	0.999
Lgra_1551	tycC_1	Lgra_1551	Lgra_0545	Saframycin Mx1 synthetase B.	Non-ribosomal peptide synthase.	0.998
Lgra_2195	Lgra_1551	Lgra_2195	Lgra_1551	acyl-CoA synthetase.	Saframycin Mx1 synthetase B.	0.998
Lgra_2195	aes	Lgra_2195	Lgra_1356	acyl-CoA synthetase.	Lipase.	0.924
Lgra_2195	nqo1	Lgra_2195	Lgra_0996	acyl-CoA synthetase.	NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.	0.861
Lgra_2195	nuoE	Lgra_2195	Lgra_0997	acyl-CoA synthetase.	NADH dehydrogenase I chain E.	0.885
Lgra_2195	nuoG	Lgra_2195	Lgra_0995	acyl-CoA synthetase.	NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.	0.862
Lgra_2195	nuoI	Lgra_2195	Lgra_0993	acyl-CoA synthetase.	NADH-quinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.900
Lgra_2195	petA	Lgra_2195	Lgra_0698	acyl-CoA synthetase.	Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.	0.865
Lgra_2195	petC	Lgra_2195	Lgra_0696	acyl-CoA synthetase.	Ubiquinol-cytochrome c oxydoreductase, cytochrome c1.	0.862
Lgra_2195	pksJ_2	Lgra_2195	Lgra_1354	acyl-CoA synthetase.	Polyketide synthase module; Belongs to the ATP-dependent AMP-binding enzyme family.	0.999
Lgra_2195	tycC_1	Lgra_2195	Lgra_0545	acyl-CoA synthetase.	Non-ribosomal peptide synthase.	0.999