STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
puuAGlutamine synthase; Belongs to the glutamine synthetase family. (456 aa)    
Predicted Functional Partners:
gabD1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
  0.929
mdh_2
Alcohol dehydrogenase.
 
  
 0.923
putA
Bifunctional PutA protein (proline dehydrogenase/ delta-1-pyrroline-5-carboxylate dehydrogenase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
 0.891
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
 0.884
glsA1
Glutaminase; Belongs to the glutaminase family.
    
 0.882
hutG
Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
     
 0.879
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.878
glnA
Glutamine synthetase.
  
  
 
0.875
carA
Carbamoyl-phosphate synthetase, glutamine (small subunit); Belongs to the CarA family.
  
 
 0.872
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.871
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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