Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gloBHydroxyacylglutathione hydrolase (glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (252 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase.
 
 0.949
moeZ_1
Thiazole biosynthesis adenylyltransferase ThiF.
 
 0.914
rlmJ
Protein involved in catabolism of external DNA; Specifically methylates the adenine in position 2030 of 23S rRNA.
       0.842
Lgra_1754
Hypothetical protein.
       0.728
mltD
Membrane-bound lytic murein transglycosylase D.
       0.681
Lgra_0867
Intracellular protease/amidase.
    
 0.672
Lgra_1964
NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
  
 
  0.588
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
 
   
 0.528
Lgra_2195
acyl-CoA synthetase.
 
 
 
 0.512
gor
Glutathione reductase.
 
   
 0.470
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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