STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mutHDNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. (223 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
    
 
 0.955
Lgra_1978
Mechanosensitive ion channel MscS.
     
 0.856
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.842
Lgra_1980
Transmembrane protein.
       0.804
Lgra_1981
Zinc ribbon domain protein.
       0.804
dam
DNA adenine methylase.
 
   
 0.799
proQ_1
Hypothetical protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
     0.576
bioH
Biotin biosynthesis protein BioH.
 
     0.539
zipA
Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
    0.494
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
   
 0.493
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.