STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plaPlasminogen activator protein. (329 aa)    
Predicted Functional Partners:
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.880
minE
Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.869
pieE_2
Substrate of the Dot/Icm secretion system.
  
     0.744
Lgra_1429
Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.742
Lgra_2381
Calcium-transporting ATPase.
  
     0.739
Lgra_2360
Hypothetical protein.
  
     0.733
Lgra_2787
Ankyrin repeat protein.
  
     0.730
Lgra_2200
2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase.
  
     0.721
bcp
Acetylpolyamine aminohydrolase.
  
     0.713
kinE
Sensor histidine kinase.
  
     0.689
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.