Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DWF7-dehydrocholesterol reductase. (431 aa)    
Predicted Functional Partners:
ptp
Serine carboxypeptidase.
  
     0.740
Lgra_2291
Leucine-rich repeat-containing protein (substrate of the Dot/Icm secretion system).
  
 
   0.736
legL1
Gala protein type 1, 3 or 4.
  
     0.725
Lgra_1494
3-oxo-5-alpha-steroid 4-dehydrogenase.
  
     0.724
Lgra_2849
PPR repeat protein.
 
     0.720
Lgra_1543
Protein phosphatase 2C.
  
     0.719
Lgra_0492
PPR repeat protein.
 
     0.694
Lgra_0246
tRNA modification GTPase TrmE.
  
 
  0.673
Lgra_2082
Serine carboxypeptidase.
  
     0.656
Lgra_2421
Ras family protein.
  
 
  0.624
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.