rihA protein (Legionella gratiana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

rihA

Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. (335 aa)

Predicted Functional Partners:

proP_2

0.862

iolCB

0.795

polA

0.671

udk_1

0.667

udk_2

0.667

add_1

0.667

xapA

0.655

cdd

0.644

add_2

0.620

yjjG

0.619

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
add_1	add_2	Lgra_2752	Lgra_2792	Adenosine deaminase.	Adenosine deaminase.	0.849
add_1	iolCB	Lgra_2752	Lgra_2475	Adenosine deaminase.	IolC/IolB transferase kinase protein.	0.612
add_1	rihA	Lgra_2752	Lgra_2248	Adenosine deaminase.	Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family.	0.667
add_1	xapA	Lgra_2752	Lgra_0293	Adenosine deaminase.	Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.940
add_2	add_1	Lgra_2792	Lgra_2752	Adenosine deaminase.	Adenosine deaminase.	0.849
add_2	iolCB	Lgra_2792	Lgra_2475	Adenosine deaminase.	IolC/IolB transferase kinase protein.	0.510
add_2	rihA	Lgra_2792	Lgra_2248	Adenosine deaminase.	Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family.	0.620
add_2	xapA	Lgra_2792	Lgra_0293	Adenosine deaminase.	Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.931
cdd	iolCB	Lgra_0294	Lgra_2475	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	IolC/IolB transferase kinase protein.	0.450
cdd	rihA	Lgra_0294	Lgra_2248	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family.	0.644
cdd	udk_1	Lgra_0294	Lgra_1278	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Uridine kinase.	0.932
cdd	udk_2	Lgra_0294	Lgra_1646	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Uridine kinase.	0.932
cdd	xapA	Lgra_0294	Lgra_0293	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.971
cdd	yjjG	Lgra_0294	Lgra_2068	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Haloacid dehalogenase.	0.579
iolCB	add_1	Lgra_2475	Lgra_2752	IolC/IolB transferase kinase protein.	Adenosine deaminase.	0.612
iolCB	add_2	Lgra_2475	Lgra_2792	IolC/IolB transferase kinase protein.	Adenosine deaminase.	0.510
iolCB	cdd	Lgra_2475	Lgra_0294	IolC/IolB transferase kinase protein.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.450
iolCB	rihA	Lgra_2475	Lgra_2248	IolC/IolB transferase kinase protein.	Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family.	0.795
iolCB	udk_1	Lgra_2475	Lgra_1278	IolC/IolB transferase kinase protein.	Uridine kinase.	0.420
iolCB	udk_2	Lgra_2475	Lgra_1646	IolC/IolB transferase kinase protein.	Uridine kinase.	0.420