Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lgra_2377Putative virulence protein. (467 aa)    
Predicted Functional Partners:
ubiC
4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
  
     0.753
Lgra_1223
General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.748
Lgra_0455
Ankyrin repeats (3 copies).
  
     0.747
dotA
Defect in organelle trafficking protein DotA.
  
     0.737
secA_3
Coiled-coil protein.
  
     0.737
Lgra_1224
General secretion pathway protein.
  
     0.735
Lgra_2875
Sphingomyelin phosphodiesterase.
  
     0.724
Lgra_1596
cNMP binding domain-containing protein.
 
     0.721
Lgra_1139
Putative helicase/relaxase.
  
     0.718
Lgra_2787
Ankyrin repeat protein.
  
     0.710
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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