ppaX protein (Legionella gratiana) - STRING interaction network

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[Homology]

Score

ppaX

HAD-superfamily hydrolase. (213 aa)

Predicted Functional Partners:

Lgra_3397

0.917

ribD

0.585

Lgra_1964

0.583

guaA

0.574

Lgra_2406

0.525

Lgra_0878

0.495

anmK

0.489

rpe

0.474

ppa

0.451

Lgra_0573

0.446

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lgra_0573	Lgra_1964	Lgra_0573	Lgra_1964	Cytokinin oxidase.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.520
Lgra_0573	Lgra_3397	Lgra_0573	Lgra_3397	Cytokinin oxidase.	Phosphatase.	0.446
Lgra_0573	ppaX	Lgra_0573	Lgra_2407	Cytokinin oxidase.	HAD-superfamily hydrolase.	0.446
Lgra_0878	Lgra_3397	Lgra_0878	Lgra_3397	Putative phosphotransferase.	Phosphatase.	0.534
Lgra_0878	ppaX	Lgra_0878	Lgra_2407	Putative phosphotransferase.	HAD-superfamily hydrolase.	0.495
Lgra_1964	Lgra_0573	Lgra_1964	Lgra_0573	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Cytokinin oxidase.	0.520
Lgra_1964	Lgra_3397	Lgra_1964	Lgra_3397	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Phosphatase.	0.584
Lgra_1964	ppaX	Lgra_1964	Lgra_2407	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	HAD-superfamily hydrolase.	0.583
Lgra_2406	ppaX	Lgra_2406	Lgra_2407	Hypothetical protein.	HAD-superfamily hydrolase.	0.525
Lgra_3397	Lgra_0573	Lgra_3397	Lgra_0573	Phosphatase.	Cytokinin oxidase.	0.446
Lgra_3397	Lgra_0878	Lgra_3397	Lgra_0878	Phosphatase.	Putative phosphotransferase.	0.534
Lgra_3397	Lgra_1964	Lgra_3397	Lgra_1964	Phosphatase.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.584
Lgra_3397	guaA	Lgra_3397	Lgra_2459	Phosphatase.	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.574
Lgra_3397	ppa	Lgra_3397	Lgra_0978	Phosphatase.	Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.	0.444
Lgra_3397	ppaX	Lgra_3397	Lgra_2407	Phosphatase.	HAD-superfamily hydrolase.	0.917
Lgra_3397	ribD	Lgra_3397	Lgra_1638	Phosphatase.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.585
anmK	ppaX	Lgra_3196	Lgra_2407	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	HAD-superfamily hydrolase.	0.489
guaA	Lgra_3397	Lgra_2459	Lgra_3397	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Phosphatase.	0.574
guaA	ppaX	Lgra_2459	Lgra_2407	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	HAD-superfamily hydrolase.	0.574
guaA	ribD	Lgra_2459	Lgra_1638	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.540