Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilZ_1Type IV pilus assembly PilZ. (185 aa)    
Predicted Functional Partners:
spo0F
Hypothetical protein.
  
 
 0.846
gmr_4
Hypothetical protein.
  
 
 0.846
gmr_3
GGDEF domain-containing sensory box protein.
  
 
 0.846
Lgra_2952
DamX-related protein.
  
     0.760
secA_3
Coiled-coil protein.
  
     0.757
Lgra_0455
Ankyrin repeats (3 copies).
  
     0.753
iraA
Small-molecule methyltransferase IraA.
  
     0.748
yggX
Protein that protects iron-sulfur proteins against oxidative damage; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
       0.732
Lgra_2875
Sphingomyelin phosphodiesterase.
  
     0.727
cheA
Chemotaxis histidine kinase.
  
  
 0.706
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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