Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lgra_2489Ferredoxin II (4Fe-4S); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (109 aa)    
Predicted Functional Partners:
Lgra_2054
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 0.997
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.937
porB
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 0.895
yoaA
ATP-dependent helicase.
       0.842
Lgra_2491
Glycoprotease.
       0.842
lpxK_2
tetraacyldisaccharide-1-P-4'-kinase; Belongs to the UPF0434 family.
       0.836
fadH
2,4-dienoyl-CoA reductase.
  
 0.739
hmp
Oxidoreductase, FAD-binding protein.
    
 0.734
pdhB_2
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
     
 0.689
pta
Phosphate acetyl/butaryl transferase.
    
 0.687
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
Server load: low (36%) [HD]