STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilE_2Tfp pilus assembly protein, major type IV pilin class A; Belongs to the N-Me-Phe pilin family. (143 aa)    
Predicted Functional Partners:
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
   
 0.795
pilE_1
Type-IV pilin.
 
  
 0.702
bolA
Regulator of penicillin binding proteins and beta lactamase transcription (morphogene); Belongs to the BolA/IbaG family.
       0.644
pilD
Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.577
pilC
Pilus assembly protein PilC.
 
   
 0.565
pilM
Tfp pilus assembly protein, ATPase PilM.
 
   
 0.554
pilO
Tfp pilus assembly protein PilO.
  
   
 0.508
Lgra_3146
Ankyrin repeat-containing protein.
    
   0.500
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
      
 0.492
Lgra_3389
Type IV fimbrial biogenesis PilY1-like protein.
 
   
 0.488
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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