STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fleRTwo-component response regulator. (437 aa)    
Predicted Functional Partners:
fleS
Sensor histidine kinase.
 0.994
rpoN
RNA polymerase sigma-54 factor (sigma-L); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.976
fleN
Flagellar synthesis regulator.
 
 
 0.971
flgD
Flagellar basal body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.891
fliA
Sigma factor 28; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.877
bvgS
Sensory box histidine kinase/response regulator.
 
 0.849
arcB_3
Sensory histidine-kinase / response regulator.
 
 0.846
evgS
Sensory box histidine kinase/response regulator.
 
 0.841
cheA
Chemotaxis histidine kinase.
 
 0.787
luxQ
Sensor histidine kinase.
  
 0.786
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.