STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fleRTwo-component response regulator. (437 aa)    
Predicted Functional Partners:
fleS
Sensor histidine kinase.
 0.976
fleN
Flagellar synthesis regulator.
 
 0.966
rpoN
RNA polymerase sigma-54 factor (sigma-L); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.955
cheA
Chemotaxis histidine kinase.
 
 0.934
bvgS
Sensory box histidine kinase/response regulator.
 
 0.871
arcB_3
Sensory histidine-kinase / response regulator.
 
 0.868
flgD
Flagellar basal body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.852
evgS
Sensory box histidine kinase/response regulator.
 
 0.850
letS
Legionella transmission sensor LetS.
 
 0.835
luxQ
Sensor histidine kinase.
 
0.828
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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