Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lgra_2627Phage repressor. (227 aa)    
Predicted Functional Partners:
lvrA_1
Legionella vir region protein.
 
     0.868
lvrA_2
Protein LvrA.
  
     0.726
Lgra_2160
Protein-tyrosine phosphatase.
  
     0.675
Lgra_0067
Initiator Replication protein.
  
     0.643
Lgra_0335
Hypothetical protein.
  
     0.642
Lgra_0604
IcmF.
  
     0.629
dotA
Defect in organelle trafficking protein DotA.
  
     0.600
Lgra_1995
uracil-DNA glycosylase.
  
    0.594
Lgra_2054
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.577
Lgra_1500
Opacity protein-like surface antigen.
  
     0.567
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
Server load: medium (60%) [HD]