Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lgra_2875Sphingomyelin phosphodiesterase. (383 aa)    
Predicted Functional Partners:
Lgra_2787
Ankyrin repeat protein.
  
 
   0.803
dacB_1
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.
 
     0.790
Lgra_0455
Ankyrin repeats (3 copies).
  
     0.772
secA_3
Coiled-coil protein.
  
     0.772
SidM_3
Hypothetical protein.
  
     0.772
iraA
Small-molecule methyltransferase IraA.
  
     0.768
Lgra_0805
CAAX amino terminal protease self- immunity.
 
     0.767
Lgra_1596
cNMP binding domain-containing protein.
  
     0.764
Lgra_1139
Putative helicase/relaxase.
  
     0.756
aprX
Subtilisin-like serine protease.
  
     0.753
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.