Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lgra_2880Putative biotin synthetase like protein. (413 aa)    
Predicted Functional Partners:
ribA_1
GTP cyclohydrolase II.
     0.994
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.907
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
     0.817
ribE
Riboflavin synthase alpha chain.
  
 0.772
evgS
Sensory box histidine kinase/response regulator.
   
  0.708
bvgS
Sensory box histidine kinase/response regulator.
  
 
  0.702
arcB_3
Sensory histidine-kinase / response regulator.
  
 
  0.702
Lgra_1232
6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.
  
 
  0.691
ribH1
6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.
  
 
  0.691
spo0F
Hypothetical protein.
 
  
 0.630
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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