ribA_1 protein (Legionella gratiana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ribA_1

GTP cyclohydrolase II. (422 aa)

Predicted Functional Partners:

Lgra_2880

0.994

ribD

0.947

ribE

0.897

evgS

0.860

ribH1

0.850

upp

0.808

Lgra_1232

0.791

bvgS

0.766

arcB_3

0.766

gmr_1

0.731

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lgra_1232	Lgra_2880	Lgra_1232	Lgra_2880	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	Putative biotin synthetase like protein.	0.691
Lgra_1232	ribA_1	Lgra_1232	Lgra_2881	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	GTP cyclohydrolase II.	0.791
Lgra_1232	ribD	Lgra_1232	Lgra_1638	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.940
Lgra_1232	ribE	Lgra_1232	Lgra_1055	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	Riboflavin synthase alpha chain.	0.967
Lgra_1232	ribH1	Lgra_1232	Lgra_1233	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	0.856
Lgra_2880	Lgra_1232	Lgra_2880	Lgra_1232	Putative biotin synthetase like protein.	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	0.691
Lgra_2880	arcB_3	Lgra_2880	Lgra_2314	Putative biotin synthetase like protein.	Sensory histidine-kinase / response regulator.	0.702
Lgra_2880	bvgS	Lgra_2880	Lgra_1355	Putative biotin synthetase like protein.	Sensory box histidine kinase/response regulator.	0.702
Lgra_2880	evgS	Lgra_2880	Lgra_0609	Putative biotin synthetase like protein.	Sensory box histidine kinase/response regulator.	0.708
Lgra_2880	gmr_1	Lgra_2880	Lgra_2086	Putative biotin synthetase like protein.	Inner membrane protein.	0.622
Lgra_2880	ribA_1	Lgra_2880	Lgra_2881	Putative biotin synthetase like protein.	GTP cyclohydrolase II.	0.994
Lgra_2880	ribD	Lgra_2880	Lgra_1638	Putative biotin synthetase like protein.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.907
Lgra_2880	ribE	Lgra_2880	Lgra_1055	Putative biotin synthetase like protein.	Riboflavin synthase alpha chain.	0.772
Lgra_2880	ribH1	Lgra_2880	Lgra_1233	Putative biotin synthetase like protein.	6,7-dimethyl-8-ribityllumazine synthase; Belongs to the DMRL synthase family.	0.691
Lgra_2880	upp	Lgra_2880	Lgra_2879	Putative biotin synthetase like protein.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.817
arcB_3	Lgra_2880	Lgra_2314	Lgra_2880	Sensory histidine-kinase / response regulator.	Putative biotin synthetase like protein.	0.702
arcB_3	bvgS	Lgra_2314	Lgra_1355	Sensory histidine-kinase / response regulator.	Sensory box histidine kinase/response regulator.	0.999
arcB_3	evgS	Lgra_2314	Lgra_0609	Sensory histidine-kinase / response regulator.	Sensory box histidine kinase/response regulator.	0.999
arcB_3	gmr_1	Lgra_2314	Lgra_2086	Sensory histidine-kinase / response regulator.	Inner membrane protein.	0.984
arcB_3	ribA_1	Lgra_2314	Lgra_2881	Sensory histidine-kinase / response regulator.	GTP cyclohydrolase II.	0.766