pyrH protein (Legionella gratiana) - STRING interaction network

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pyrH

Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa)

Predicted Functional Partners:

rrf

0.987

tsf

0.986

rpsB

0.976

upp

0.975

ndk

0.955

pyrF

0.939

surE

0.895

udk_1

0.884

udk_2

0.884

yhdE

0.849

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ndk	pyrH	Lgra_2116	Lgra_3359	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.955
ndk	rpsB	Lgra_2116	Lgra_3361	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.964
ndk	tsf	Lgra_2116	Lgra_3360	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.451
ndk	yhdE	Lgra_2116	Lgra_1526	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	0.855
pyrF	pyrH	Lgra_0282	Lgra_3359	Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.939
pyrF	surE	Lgra_0282	Lgra_1737	Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Acid phosphatase SurE (Stationary phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.880
pyrF	udk_1	Lgra_0282	Lgra_1278	Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Uridine kinase.	0.857
pyrF	udk_2	Lgra_0282	Lgra_1646	Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Uridine kinase.	0.857
pyrF	upp	Lgra_0282	Lgra_2879	Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.895
pyrF	yhdE	Lgra_0282	Lgra_1526	Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	0.849
pyrH	ndk	Lgra_3359	Lgra_2116	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.955
pyrH	pyrF	Lgra_3359	Lgra_0282	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.939
pyrH	rpsB	Lgra_3359	Lgra_3361	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.976
pyrH	rrf	Lgra_3359	Lgra_3358	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	0.987
pyrH	surE	Lgra_3359	Lgra_1737	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Acid phosphatase SurE (Stationary phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.895
pyrH	tsf	Lgra_3359	Lgra_3360	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.986
pyrH	udk_1	Lgra_3359	Lgra_1278	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Uridine kinase.	0.884
pyrH	udk_2	Lgra_3359	Lgra_1646	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Uridine kinase.	0.884
pyrH	upp	Lgra_3359	Lgra_2879	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.975
pyrH	yhdE	Lgra_3359	Lgra_1526	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	0.849