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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PlaPlasminogen activator protein. (314 aa)    
Predicted Functional Partners:
legA
Ankyrin-repeat containing protein, substrate of the Dot/Icm secretion system.
  
     0.758
Nat
Putative N-hydroxyarylamine O-acetyltransferase.
  
     0.754
gntT
H gluconate symporter.
  
     0.749
Llan_1996
L-gulono-gamma-lactone oxidase.
  
     0.736
Llan_0278
Putative aminoglycoside phosphotransferase.
 
     0.726
rssA
Esterase of the alpha-beta hydrolase superfamily protein.
  
     0.717
KefA
Potassium efflux system KefA.
  
     0.689
Llan_1010
Hypothetical protein.
  
     0.685
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.671
Llan_1703
Phosphotransferase enzyme family protein.
  
     0.652
Your Current Organism:
Legionella lansingensis
NCBI taxonomy Id: 45067
Other names: ATCC 49751, CCUG 31227 B, CIP 103542, DSM 19556, L. lansingensis, NCTC 12830
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