Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BdhA_23-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)    
Predicted Functional Partners:
adc
Acetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family.
 
  
  0.988
mvaB
hydroxymethylglutaryl-CoA lyase.
   
 
  0.915
AcsA
Acetoacetyl CoA synthetase.
    
  0.900
Llan_1219
Patatin-like phospholipase.
 
 
   0.772
Llan_0801
SAM-dependent O-methyltransferase.
 
  
   0.752
Llan_0746
Hypothetical protein.
       0.674
Llan_0569
Patatin-like phospholipase.
 
 
   0.661
FadI
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.649
Llan_0132
Patatin-like phospholipase.
 
 
   0.647
Llan_0553
Alpha-beta hydrolase family transporter esterase.
 
 
   0.627
Your Current Organism:
Legionella lansingensis
NCBI taxonomy Id: 45067
Other names: ATCC 49751, CCUG 31227 B, CIP 103542, DSM 19556, L. lansingensis, NCTC 12830
Server load: low (8%) [HD]