STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
yfiHLaccase domain protein YfiH; Belongs to the multicopper oxidase YfiH/RL5 family. (251 aa)    
Predicted Functional Partners:
hpt
Hypoxanthine phosphoribosyltransferase.
  
 
  0.910
ppt
Hypoxanthine-guanine phosphoribosyltransferase.
  
 
  0.910
xapA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.902
add_1
Adenosine deaminase.
    
  0.901
add_2
Adenosine deaminase.
    
  0.901
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.900
Llan_2128
Spermidine synthase.
     
  0.900
miaB
(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
   
 0.888
rluD
Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.856
htrA
Protease DO; Belongs to the peptidase S1C family.
       0.835
Your Current Organism:
Legionella lansingensis
NCBI taxonomy Id: 45067
Other names: ATCC 49751, CCUG 31227 B, CIP 103542, DSM 19556, L. lansingensis, NCTC 12830
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