STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MrcA_2Penicillin binding protein 1C, peptidoglycan biosynthesis. (769 aa)    
Predicted Functional Partners:
Llan_1993
Hypothetical protein; Alpha-2-macroglobulin family N-terminal region.
   
 0.957
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
  
 0.937
ftsI
Peptidoglycan synthetase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
  
 0.930
ponA
Penicillin binding protein 1A.
  
  
0.925
dacB
D-alanyl-D-alanine carboxypeptidase.
   
 
 0.909
DacB_1
D-Ala-D-Ala carboxypeptidase.
   
 
 0.909
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
     
 0.905
Llan_1877
Secreted protein.
  
     0.484
Llan_1991
Hypothetical protein.
       0.452
rodA
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.423
Your Current Organism:
Legionella lansingensis
NCBI taxonomy Id: 45067
Other names: ATCC 49751, CCUG 31227 B, CIP 103542, DSM 19556, L. lansingensis, NCTC 12830
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