STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Frcacyl-CoA transferase; Belongs to the CoA-transferase III family. (384 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.915
sucC
Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.909
Mcl1
Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.878
CaiA_3
Short chain-specific acyl CoA dehydrogenase.
 
 
 0.637
pta
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.617
Llan_1423
Glutaryl CoA dehydrogenase.
 
 0.597
mvaB
hydroxymethylglutaryl-CoA lyase.
 
 
  0.502
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase.
  
 
 0.468
yfcX
Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.468
Llan_2092
Protein IcmB (DotO).
       0.432
Your Current Organism:
Legionella lansingensis
NCBI taxonomy Id: 45067
Other names: ATCC 49751, CCUG 31227 B, CIP 103542, DSM 19556, L. lansingensis, NCTC 12830
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.