fadE protein (Legionella lansingensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

fadE

acyl-CoA dehydrogenase. (830 aa)

Predicted Functional Partners:

yfcX

0.998

FadI

0.969

PcaF

0.969

fadA

0.959

fadB

0.956

atoB

0.952

CaiA_1

0.908

Llan_1423

0.900

Llan_2153

0.742

Llan_2154

0.705

Your Current Organism:

Legionella lansingensis

NCBI taxonomy Id: 45067
Other names: ATCC 49751, CCUG 31227 B, CIP 103542, DSM 19556, L. lansingensis, NCTC 12830

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CaiA_1	FadI	Llan_1736	Llan_0749	acyl-CoA dehydrogenase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.969
CaiA_1	Llan_1423	Llan_1736	Llan_1423	acyl-CoA dehydrogenase.	Glutaryl CoA dehydrogenase.	0.904
CaiA_1	PcaF	Llan_1736	Llan_1913	acyl-CoA dehydrogenase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.970
CaiA_1	atoB	Llan_1736	Llan_0032	acyl-CoA dehydrogenase.	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.952
CaiA_1	fadA	Llan_1736	Llan_1850	acyl-CoA dehydrogenase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.960
CaiA_1	fadB	Llan_1736	Llan_1851	acyl-CoA dehydrogenase.	3-hydroxyacyl CoA dehydrogenase oxidoreductase.	0.956
CaiA_1	fadE	Llan_1736	Llan_2152	acyl-CoA dehydrogenase.	acyl-CoA dehydrogenase.	0.908
CaiA_1	yfcX	Llan_1736	Llan_1914	acyl-CoA dehydrogenase.	Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.998
FadI	CaiA_1	Llan_0749	Llan_1736	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acyl-CoA dehydrogenase.	0.969
FadI	Llan_1423	Llan_0749	Llan_1423	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Glutaryl CoA dehydrogenase.	0.541
FadI	PcaF	Llan_0749	Llan_1913	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.913
FadI	atoB	Llan_0749	Llan_0032	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926
FadI	fadA	Llan_0749	Llan_1850	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.923
FadI	fadB	Llan_0749	Llan_1851	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl CoA dehydrogenase oxidoreductase.	0.999
FadI	fadE	Llan_0749	Llan_2152	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acyl-CoA dehydrogenase.	0.969
FadI	yfcX	Llan_0749	Llan_1914	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
Llan_1423	CaiA_1	Llan_1423	Llan_1736	Glutaryl CoA dehydrogenase.	acyl-CoA dehydrogenase.	0.904
Llan_1423	FadI	Llan_1423	Llan_0749	Glutaryl CoA dehydrogenase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.541
Llan_1423	PcaF	Llan_1423	Llan_1913	Glutaryl CoA dehydrogenase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.541
Llan_1423	atoB	Llan_1423	Llan_0032	Glutaryl CoA dehydrogenase.	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.595