Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)    
Predicted Functional Partners:
sdhA_2
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.996
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.985
sdhB
Succinate dehydrogenase iron-sulfur subunit.
  
 0.955
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 0.951
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
   
 0.951
SdhC
Succinate dehydrogenase cytochrome b556 subunit C.
   
 
 0.942
sfcA_1
Malate dehydrogenase.
  
 
 0.937
sfcA_2
Malate oxidoreductase.
  
 
 0.937
MaeB
NADP-dependent malic enzyme.
  
 
 0.937
ttdA
L(+)-tartrate dehydratase subunit alpha.
  
 
 0.935
Your Current Organism:
Legionella lansingensis
NCBI taxonomy Id: 45067
Other names: ATCC 49751, CCUG 31227 B, CIP 103542, DSM 19556, L. lansingensis, NCTC 12830
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