STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
acsBacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (646 aa)    
Predicted Functional Partners:
pta
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.921
yfcX
Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.915
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase.
  
 
 0.915
ack
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.835
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.834
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 0.834
pksJ
Polyketide synthase, type I.
  
 0.822
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.809
Llon_1692
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
  
 
 0.801
fadD-1
Long chain fatty acid-CoA ligase.
 
0.764
Your Current Organism:
Legionella londiniensis
NCBI taxonomy Id: 45068
Other names: ATCC 49505, CCUG 44895, CIP 105269, L. londiniensis, NCTC 12374, NCTC:13722
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