STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lnau_0065Keto-hydroxyglutarate aldolase. (189 aa)    
Predicted Functional Partners:
Lnau_2121
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.752
Lnau_2888
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
     
 0.749
gpi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.737
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
     
 0.693
tpi
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.692
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
    
 0.691
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
     
 0.690
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.684
oxdD
Oxalate decarboxylase OxdD.
    
  0.651
aceB
Malate synthase A; Belongs to the malate synthase family.
     
 0.650
Your Current Organism:
Legionella nautarum
NCBI taxonomy Id: 45070
Other names: ATCC 49506, CCUG 44900, CIP 105270, DSM 21805, L. nautarum, NCTC 12375, NCTC 12932
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