node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
rlmB | rluD | Lnau_0562 | Lnau_1163 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.933 |
rlmB | rplC | Lnau_0562 | Lnau_2248 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.946 |
rlmB | rplK | Lnau_0562 | Lnau_2237 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.959 |
rlmB | rplM | Lnau_0562 | Lnau_2984 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.948 |
rlmB | rplO | Lnau_0562 | Lnau_2267 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.932 |
rlmB | rplU | Lnau_0562 | Lnau_0353 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.935 |
rlmB | rsfS | Lnau_0562 | Lnau_1234 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.939 |
rlmB | trmE | Lnau_0562 | Lnau_1454 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.942 |
rlmB | vacB | Lnau_0562 | Lnau_0561 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.976 |
rlmB | yihA | Lnau_0562 | Lnau_1604 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.934 |
rluD | rlmB | Lnau_1163 | Lnau_0562 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.933 |
rluD | rplC | Lnau_1163 | Lnau_2248 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.897 |
rluD | rplK | Lnau_1163 | Lnau_2237 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.897 |
rluD | rplM | Lnau_1163 | Lnau_2984 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.903 |
rluD | rplO | Lnau_1163 | Lnau_2267 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.902 |
rluD | rplU | Lnau_1163 | Lnau_0353 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.919 |
rluD | rsfS | Lnau_1163 | Lnau_1234 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.919 |
rluD | trmE | Lnau_1163 | Lnau_1454 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.933 |
rluD | vacB | Lnau_1163 | Lnau_0561 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.653 |
rluD | yihA | Lnau_1163 | Lnau_1604 | Uracil hydrolyase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.894 |