node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lnau_1728 | guaA | Lnau_1728 | Lnau_1100 | Glutamine amidotransferase, class I. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.678 |
Lnau_1728 | guaB | Lnau_1728 | Lnau_1099 | Glutamine amidotransferase, class I. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.873 |
Lnau_1728 | pheT | Lnau_1728 | Lnau_2981 | Glutamine amidotransferase, class I. | phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.473 |
Lnau_1728 | purA | Lnau_1728 | Lnau_0389 | Glutamine amidotransferase, class I. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.516 |
Lnau_1728 | purB | Lnau_1728 | Lnau_0919 | Glutamine amidotransferase, class I. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.414 |
Lnau_1728 | purH | Lnau_1728 | Lnau_0418 | Glutamine amidotransferase, class I. | Phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional). | 0.485 |
Lnau_1728 | ribA | Lnau_1728 | Lnau_1052 | Glutamine amidotransferase, class I. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.424 |
guaA | Lnau_1728 | Lnau_1100 | Lnau_1728 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glutamine amidotransferase, class I. | 0.678 |
guaA | guaB | Lnau_1100 | Lnau_1099 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | pheT | Lnau_1100 | Lnau_2981 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.939 |
guaA | purA | Lnau_1100 | Lnau_0389 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.936 |
guaA | purB | Lnau_1100 | Lnau_0919 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.927 |
guaA | purH | Lnau_1100 | Lnau_0418 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional). | 0.942 |
guaA | ribA | Lnau_1100 | Lnau_1052 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.514 |
guaA | rpoB | Lnau_1100 | Lnau_2241 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.940 |
guaA | tadA | Lnau_1100 | Lnau_1101 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.882 |
guaA | tkt | Lnau_1100 | Lnau_2122 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.420 |
guaB | Lnau_1728 | Lnau_1099 | Lnau_1728 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Glutamine amidotransferase, class I. | 0.873 |
guaB | guaA | Lnau_1099 | Lnau_1100 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
guaB | pheT | Lnau_1099 | Lnau_2981 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.896 |