STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsPPhosphoenolpyruvate-protein phosphotransferase PtsP; Belongs to the PEP-utilizing enzyme family. (765 aa)    
Predicted Functional Partners:
ptsH
Sugar transport PTS system phosphocarrier HPr protein.
  
 
 0.992
nudH
Nucleotide hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
 
  0.861
cyaB_1
Guanylate/adenylate cyclase.
   
 0.806
kinB
Sensory box histidine kinase/response regulator.
   
 0.747
cya_1
Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
  0.718
cyaA_2-2
Adenylate/guanylate cyclase transmembrane protein.
    
  0.693
cyaA_1
Fused adenylate cyclase/two component hybrid sensor/regulator.
    
  0.693
ycdT_2
Diguanylate kinase.
    
  0.673
cph2_6
Regulatory protein (GGDEF and EAL domains).
    
  0.642
gmr_2
Regulatory protein (GGDEF domain).
    
  0.642
Your Current Organism:
Legionella parisiensis
NCBI taxonomy Id: 45071
Other names: ATCC 35299, CCUG 29670, CIP 103847, DSM 19216, JCM 7561, L. parisiensis, Legionella parisensis, NCTC 11983, strain PF-209C-C2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.