STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbiB_2Nitroreductase. (199 aa)    
Predicted Functional Partners:
Lpar_1623
acyl-CoA synthetase.
  
 0.876
birA
biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.769
xylA_1
Xylene monooxygenase.
    
 0.766
xylA_2
Ferredoxin reductase.
    
 0.766
Lpar_3014
acyl-CoA synthetase.
   
 0.759
moeZ_1
Thiazole biosynthesis adenylyltransferase ThiF.
    
 0.750
Lpar_3635
Polyketide synthase.
  
 0.736
hydG
Hydrogenase/sulfur reductase gamma subunit.
 
  
 0.683
Lpar_2061
Pterin-4-alpha-carbinolamine dehydratase.
   
 
  0.621
fadH
2,4-dienoyl-CoA reductase.
  
 
 0.590
Your Current Organism:
Legionella parisiensis
NCBI taxonomy Id: 45071
Other names: ATCC 35299, CCUG 29670, CIP 103847, DSM 19216, JCM 7561, L. parisiensis, Legionella parisensis, NCTC 11983, strain PF-209C-C2
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