Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lidCThiol:disulfide interchange protein DsbD. (581 aa)    
Predicted Functional Partners:
msrA_2
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
 
 0.955
ccmG
Cytochrome C biogenesis protein.
  
 
 0.939
groES
Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.893
com1
27 kDa outer membrane protein.
  
 
 0.825
dsbA
Thiol:disulfide interchange protein precursor DsbA.
 
 
 0.809
trxA
Thioredoxin; Belongs to the thioredoxin family.
   
 0.735
resA_2
Thiol-disulfide oxidoreductase.
  
 
 0.735
htpB
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
  
 0.701
dsbB
Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
   
  
 0.628
resA_1
Cytochrome C biogenesis protein.
  
 
 0.577
Your Current Organism:
Legionella parisiensis
NCBI taxonomy Id: 45071
Other names: ATCC 35299, CCUG 29670, CIP 103847, DSM 19216, JCM 7561, L. parisiensis, Legionella parisensis, NCTC 11983, strain PF-209C-C2
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