STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plaALysophospholipase A. (308 aa)    
Predicted Functional Partners:
Lpar_2250
ATPases involved in biogenesis of archaeal flagella.
       0.624
sdhA_1
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
      
 0.494
lapB
Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      
 0.491
Lpar_0591
Aminopeptidase.
  
     0.479
lspD
Type II protein secretion LspD.
   
  
 0.479
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.465
Lpar_0452
Bacterioferritin (cytochrome b1).
  
     0.453
lspI
Type II secretory pathway protein LspI.
      
 0.452
lspK
Type II secretory pathway protein LspK.
      
 0.451
proA
Zinc metalloproteinase precursor; Extracellular zinc metalloprotease.
  
   
 0.447
Your Current Organism:
Legionella parisiensis
NCBI taxonomy Id: 45071
Other names: ATCC 35299, CCUG 29670, CIP 103847, DSM 19216, JCM 7561, L. parisiensis, Legionella parisensis, NCTC 11983, strain PF-209C-C2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.