STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lssALegionella secretion system protein A. (233 aa)    
Predicted Functional Partners:
dedE
Colicin V.
      
 0.671
lapB
Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      
 0.663
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
    
 0.663
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.641
Lpar_2516
Type I secretion system LssZ.
       0.561
dacB_1
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.
    
  0.496
dacB_2
D-Ala-D-Ala carboxypeptidase.
    
  0.496
ftsI
Transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.455
dacC_2
Serine-type D-Ala-D-Ala carboxypeptidase.
    
  0.422
rna
Ribonuclease T2 family protein; Belongs to the RNase T2 family.
  
     0.410
Your Current Organism:
Legionella parisiensis
NCBI taxonomy Id: 45071
Other names: ATCC 35299, CCUG 29670, CIP 103847, DSM 19216, JCM 7561, L. parisiensis, Legionella parisensis, NCTC 11983, strain PF-209C-C2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.