node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dadA | iscS | Lpar_2600 | Lpar_2825 | FAD dependent oxidoreductase. | Cysteine desulfurase. | 0.535 |
dadA | moeZ_1 | Lpar_2600 | Lpar_3291 | FAD dependent oxidoreductase. | Thiazole biosynthesis adenylyltransferase ThiF. | 0.690 |
dadA | thiDE | Lpar_2600 | Lpar_3292 | FAD dependent oxidoreductase. | Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.672 |
dadA | thiG | Lpar_2600 | Lpar_3293 | FAD dependent oxidoreductase. | Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.801 |
dadA | thiS | Lpar_2600 | Lpar_3294 | FAD dependent oxidoreductase. | Thiamine biosynthesis protein ThiS. | 0.655 |
iscS | dadA | Lpar_2825 | Lpar_2600 | Cysteine desulfurase. | FAD dependent oxidoreductase. | 0.535 |
iscS | mnmC_1 | Lpar_2825 | Lpar_2680 | Cysteine desulfurase. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.682 |
iscS | moeZ_1 | Lpar_2825 | Lpar_3291 | Cysteine desulfurase. | Thiazole biosynthesis adenylyltransferase ThiF. | 0.962 |
iscS | thiG | Lpar_2825 | Lpar_3293 | Cysteine desulfurase. | Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.697 |
iscS | thiO | Lpar_2825 | Lpar_3295 | Cysteine desulfurase. | Thiamine biosynthesis oxidoreductase ThiO. | 0.535 |
mnmC_1 | iscS | Lpar_2680 | Lpar_2825 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Cysteine desulfurase. | 0.682 |
mnmC_1 | moeZ_1 | Lpar_2680 | Lpar_3291 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Thiazole biosynthesis adenylyltransferase ThiF. | 0.693 |
mnmC_1 | thiDE | Lpar_2680 | Lpar_3292 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.674 |
mnmC_1 | thiG | Lpar_2680 | Lpar_3293 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.671 |
mnmC_1 | thiS | Lpar_2680 | Lpar_3294 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Thiamine biosynthesis protein ThiS. | 0.651 |
moeZ_1 | dadA | Lpar_3291 | Lpar_2600 | Thiazole biosynthesis adenylyltransferase ThiF. | FAD dependent oxidoreductase. | 0.690 |
moeZ_1 | iscS | Lpar_3291 | Lpar_2825 | Thiazole biosynthesis adenylyltransferase ThiF. | Cysteine desulfurase. | 0.962 |
moeZ_1 | mnmC_1 | Lpar_3291 | Lpar_2680 | Thiazole biosynthesis adenylyltransferase ThiF. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.693 |
moeZ_1 | thiD | Lpar_3291 | Lpar_1993 | Thiazole biosynthesis adenylyltransferase ThiF. | Bifunctional hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase. | 0.844 |
moeZ_1 | thiDE | Lpar_3291 | Lpar_3292 | Thiazole biosynthesis adenylyltransferase ThiF. | Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.994 |