| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | etfA | Lqua_1116 | Lqua_2634 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Electron transfer flavoprotein subunit alpha. | 0.605 |
| aceF | fumC | Lqua_1116 | Lqua_2769 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.440 |
| aceF | odp2 | Lqua_1116 | Lqua_1193 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.631 |
| aceF | sdhA_2 | Lqua_1116 | Lqua_0550 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.852 |
| aceF | sdhB_1 | Lqua_1116 | Lqua_0549 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase iron-sulfur subunit. | 0.905 |
| aceF | sdhC | Lqua_1116 | Lqua_0552 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase cytochrome b556 subunit C. | 0.506 |
| aceF | sucA | Lqua_1116 | Lqua_0548 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component. | 0.999 |
| aceF | sucC | Lqua_1116 | Lqua_0546 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.963 |
| aceF | sucD | Lqua_1116 | Lqua_0545 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.953 |
| etfA | aceF | Lqua_2634 | Lqua_1116 | Electron transfer flavoprotein subunit alpha. | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.605 |
| etfA | fumC | Lqua_2634 | Lqua_2769 | Electron transfer flavoprotein subunit alpha. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.775 |
| etfA | odp2 | Lqua_2634 | Lqua_1193 | Electron transfer flavoprotein subunit alpha. | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.605 |
| etfA | sdhA_2 | Lqua_2634 | Lqua_0550 | Electron transfer flavoprotein subunit alpha. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.443 |
| etfA | sdhB_1 | Lqua_2634 | Lqua_0549 | Electron transfer flavoprotein subunit alpha. | Succinate dehydrogenase iron-sulfur subunit. | 0.657 |
| etfA | sdhC | Lqua_2634 | Lqua_0552 | Electron transfer flavoprotein subunit alpha. | Succinate dehydrogenase cytochrome b556 subunit C. | 0.535 |
| etfA | sucB | Lqua_2634 | Lqua_0547 | Electron transfer flavoprotein subunit alpha. | Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.605 |
| etfA | sucC | Lqua_2634 | Lqua_0546 | Electron transfer flavoprotein subunit alpha. | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.689 |
| etfA | sucD | Lqua_2634 | Lqua_0545 | Electron transfer flavoprotein subunit alpha. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.924 |
| fumC | aceF | Lqua_2769 | Lqua_1116 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.440 |
| fumC | etfA | Lqua_2769 | Lqua_2634 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Electron transfer flavoprotein subunit alpha. | 0.775 |