Hgd protein (Legionella quateirensis) - STRING interaction network

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Score

Hgd

3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (298 aa)

Predicted Functional Partners:

echA8_2

0.997

acsB_1

0.904

mmsA

0.892

yfcX

0.839

fadB

0.839

pheA

0.732

ydiJ

0.712

echA8_1

0.696

echA8_3

0.696

mccB

0.676

Your Current Organism:

Legionella quateirensis

NCBI taxonomy Id: 45072
Other names: ATCC 49507, CCUG 44899, CIP 105271, L. quateirensis, NCTC 12376

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hgd	acsB_1	Lqua_0745	Lqua_0746	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.904
Hgd	echA8_1	Lqua_0745	Lqua_1464	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Enoyl CoA hydratase/isomerase (crotonase).	0.696
Hgd	echA8_2	Lqua_0745	Lqua_2124	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Enoyl-CoA hydratase/carnithine racemase.	0.997
Hgd	echA8_3	Lqua_0745	Lqua_2123	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	3-hydroxyisobutyryl-CoA hydrolase.	0.696
Hgd	fadB	Lqua_0745	Lqua_3105	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	3-hydroxyacyl CoA dehydrogenase oxidoreductase protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.839
Hgd	mccB	Lqua_0745	Lqua_1463	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Propionyl CoA carboxylase subunit beta.	0.676
Hgd	mmsA	Lqua_0745	Lqua_0744	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Methylmalonate-semialdehyde dehydrogenase.	0.892
Hgd	pheA	Lqua_0745	Lqua_3332	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	2-methylcitrate synthase.	0.732
Hgd	ydiJ	Lqua_0745	Lqua_0217	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Oxidase.	0.712
Hgd	yfcX	Lqua_0745	Lqua_1232	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.839
acsB_1	Hgd	Lqua_0746	Lqua_0745	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.904
acsB_1	echA8_1	Lqua_0746	Lqua_1464	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Enoyl CoA hydratase/isomerase (crotonase).	0.516
acsB_1	echA8_2	Lqua_0746	Lqua_2124	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Enoyl-CoA hydratase/carnithine racemase.	0.559
acsB_1	echA8_3	Lqua_0746	Lqua_2123	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	3-hydroxyisobutyryl-CoA hydrolase.	0.519
acsB_1	fadB	Lqua_0746	Lqua_3105	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	3-hydroxyacyl CoA dehydrogenase oxidoreductase protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.974
acsB_1	mmsA	Lqua_0746	Lqua_0744	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Methylmalonate-semialdehyde dehydrogenase.	0.845
acsB_1	ydiJ	Lqua_0746	Lqua_0217	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Oxidase.	0.426
acsB_1	yfcX	Lqua_0746	Lqua_1232	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.974
echA8_1	Hgd	Lqua_1464	Lqua_0745	Enoyl CoA hydratase/isomerase (crotonase).	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.696
echA8_1	acsB_1	Lqua_1464	Lqua_0746	Enoyl CoA hydratase/isomerase (crotonase).	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.516