Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cph2_1Diguanylate cyclase/phosphodiesterase domain 2. (549 aa)    
Predicted Functional Partners:
dosC
Regulatory protein (GGDEF, PAS, PAC domains).
 
 0.897
csrD
Two component histidine kinase.
 
 0.892
cph2_3
Inner membrane protein/sensory box protein LssE.
 
0.843
gmr_7
Regulatory protein (GGDEF domain).
 
0.829
ycdT
Sensor histidine kinase.
 
 
 0.804
ycgG_1
Signal transduction protein (EAL/GGDEF domain protein).
  
 
  0.799
pleD_4
Diguanylate kinase.
  
 
   0.790
Lqua_0806
Cupin domain protein.
       0.781
cph2_2
Regulatory protein (GGDEF, EAL, PAS and PAC domains).
  
     0.765
pleD_1
Regulatory protein (GGDEF domain).
  
     0.765
Your Current Organism:
Legionella quateirensis
NCBI taxonomy Id: 45072
Other names: ATCC 49507, CCUG 44899, CIP 105271, L. quateirensis, NCTC 12376
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