STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (342 aa)    
Predicted Functional Partners:
mvaA
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
   
 0.959
ydiJ
Oxidase.
  
 0.914
Lqua_2670
Mevalonate diphosphate decarboxylase.
 
  
 0.909
Lqua_0854
Hypothetical protein.
    
 0.878
Lqua_2669
Putative mevalonate kinase.
 
  
 0.859
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.837
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.779
Lqua_2510
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.753
pdhB_1
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
    
 0.663
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
   
 0.651
Your Current Organism:
Legionella quateirensis
NCBI taxonomy Id: 45072
Other names: ATCC 49507, CCUG 44899, CIP 105271, L. quateirensis, NCTC 12376
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