STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepN_1Aminopeptidase N. (891 aa)    
Predicted Functional Partners:
fadH
2,4-dienoyl-CoA reductase FadH1.
    
 
 0.746
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.622
pepA
Leucine aminopeptidase; Belongs to the peptidase M17 family.
   
 0.591
pepA-2
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.591
Lqua_1869
Serine/threonine protein kinase.
  
 
 0.587
pepN
Aminopeptidase.
  
  
 
0.579
cysK
Cystathionine beta synthase.
 
   
 0.552
Lqua_1483
Glutamate--cysteine ligase.
   
 
  0.541
ggt
Gamma-glutamyltranspeptidase.
     
 0.524
metC
Cystathionine beta-lyase.
     
 0.524
Your Current Organism:
Legionella quateirensis
NCBI taxonomy Id: 45072
Other names: ATCC 49507, CCUG 44899, CIP 105271, L. quateirensis, NCTC 12376
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