STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEPyruvate dehydrogenase E1 component oxidoreductase protein AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)    
Predicted Functional Partners:
aceF
Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.998
odp2
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.982
sucB
Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.981
lpdA
Dihydrolipoamide dehydrogenase.
 
 
 0.977
pta_1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.839
pta_2
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.839
pdhB_1
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
    
 0.833
sucA
2-oxoglutarate dehydrogenase E1 component.
  
  
 0.831
merA
Hypothetical protein.
  
 
 0.819
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.798
Your Current Organism:
Legionella quateirensis
NCBI taxonomy Id: 45072
Other names: ATCC 49507, CCUG 44899, CIP 105271, L. quateirensis, NCTC 12376
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